Shijiazhuang Yiling Pharmaceutical Co., Ltd.Lianhua Qingwen Capsules 0.35g*36 Tablets

Indications of Lianhua Qingwen Capsules

1. Influenza and Influenza-Like Illnesses

• Primary Conditions:
  • Influenza A/B (seasonal flu), viral influenza-like illnesses, and febrile respiratory infections with wind-heat characteristics.
• Symptomatic Relief:
  • High fever, chills, headache, body aches, sore throat, cough with yellow phlegm, and nasal congestion.
• Clinical Evidence:
  • Studies show efficacy in reducing fever duration, alleviating cough, and improving overall recovery in influenza patients, especially when used within 48 hours of symptom onset.

2. Wind-Heat Type Common Cold

• Syndrome Differentiation:
  • Characterized by fever (often mild to moderate), sore throat, yellow nasal discharge, dry cough, and thirst—contrasted with "wind-cold" colds (no sweating, clear mucus).
• Target Symptoms:
  • Red, swollen throat; cough with thick, yellow sputum; headache with a heavy sensation; and dry mouth.
• Herbal Mechanism:
  • Ingredients like Forsythia suspensa and Lonicera japonica clear heat and detoxify, while Ephedra sinica relieves exterior symptoms (fever, chills) and promotes diaphoresis.

3. Adjuvant Treatment for Pneumonia

• Combination Therapy:
  • As an adjunct to antibiotic/antiviral therapy in mild to moderate pneumonia (viral or bacterial) with wind-heat syndrome, especially:
    • Lung infections with fever, cough, shortness of breath, and chest discomfort.
• Supportive Effects:
  • Reduces inflammatory response, promotes expectoration, and improves pulmonary function indices (e.g., oxygen saturation).

4. Upper Respiratory Tract Infections (URTIs)

• Applicable Scenarios:
  • Acute pharyngitis, tonsillitis, and laryngitis with wind-heat symptoms (e.g., red, swollen tonsils; purulent exudate; severe sore throat).
• Symptom Management:
  • Alleviates throat pain, reduces tonsillar swelling, and inhibits bacterial adhesion (in vitro studies suggest antibacterial effects against Streptococcus pyogenes).

5. Fever Management in Infectious Diseases

• Fever Types:
  • Persistent or remittent fever due to viral/bacterial infections, especially when accompanied by:
    • Red tongue with yellow coating, rapid pulse, and signs of internal heat.
• Therapeutic Action:
  • Induces sweating to reduce fever (Ephedra and Armeniaca amarum), while Isatis root and Honeysuckle cool blood and clear toxins.

Ingredient Synergy and Mechanism

Administration and Safety Guidelines

• Dosage and Use:
  • Adults: 4 capsules orally, 3 times daily; children (6–12 years): half dosage; consult a pediatrician for ages <6 years.
• Contraindications:
  • Hypersensitivity to any ingredient; "wind-cold" colds (symptoms: no fever, clear nasal discharge, aversion to cold); pregnant/lactating women (use under medical supervision).
• Precautions:
  • Avoid spicy, oily foods; do not use with other heat-clearing medicines to prevent excessive coldness in the body.
  • Discontinue if fever persists >3 days, or symptoms worsen (e.g., shortness of breath, chest pain).

Clinical Evidence and Limitations

• Evidence Base:
  • Multiple randomized controlled trials in China show Lianhua Qingwen reduces fever duration by 1–2 days and improves cough, sore throat, and fatigue in influenza patients.
• Limitations:
  • Not a substitute for influenza vaccines or antiviral drugs (e.g., oseltamivir) in severe cases; efficacy for novel respiratory viruses (e.g., COVID-19) requires further validation beyond initial clinical trials.
• Differential Diagnosis:
  • Not indicated for bacterial infections (e.g., strep throat) as sole therapy; use with antibiotics if bacterial superinfection is suspected.