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Entrectinib 100mg*60 Capsules for NTRK Fusion Solid Tumors

Brand Name:	PHOENTRE
Model Number:	RXDX-101
MOQ:	1 PCS
Price:	Please contact a specialist WhatsApp：55342706
Delivery Time:	Negotiable
Payment Terms:	Western Union,MoneyGram,T/T

Detail Information

Product Description

Detail Information

Place of Origin:

Laos

Specifications::

100mg*60 Capsules/bottle (box)

Indications:

Kidney Cancer, Thyroid Cancer, Liver Cancer, Soft Tissue Sarcoma, Non-small Cell Lung Cancer, Prostate Cancer, Breast Cancer, Ovarian Cancer, Bowel Cancer

Target:

NRTK1/2/3、ALK、ROS1

Product Name:

Entrectinib

Recommended Dose:

Please Follow Doctor's Advice

Storage:

Sealed And Stored No More Than 30℃.

Packaging Details:

Negotiable

Supply Ability:

Negotiable

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Product Description

Entrectinib (Rozlytrek®) 200mg*90 tablets

Pan-tumor targeting immune drug for stage 1, 2, 3 cancer treatment. Targets NRTK1/2/3, ALK, ROS1.

Product Specifications

Attribute	Value
Specifications	100mg*60 capsules/bottle (box)
Indications	Kidney cancer, thyroid cancer, liver cancer, soft tissue sarcoma, non-small cell lung cancer, prostate cancer, breast cancer, ovarian cancer, bowel cancer
Target	NRTK1/2/3, ALK, ROS1
Product name	Entrectinib
Recommended dose	Please follow doctor's advice
Storage	Sealed and stored no more than 30℃

Drug Information

Generic name: Entrectinib capsules

Product name: Rozlytrek®

Chinese Pinyin: Enqutini Jiaonan

Indications

Solid tumors: Suitable for adults and children aged 12+ with solid tumors who have NTRK fusion gene confirmed by validated test, with locally advanced/metastatic disease or where surgery may cause serious complications, and no satisfactory alternative treatments.

Non-small cell lung cancer (NSCLC): For adult patients with ROS1-positive locally advanced or metastatic NSCLC.

This indication has been conditionally approved based on surrogate endpoints. Clinical endpoint data not yet available.

Dosage Information

Treatment should be initiated by physician experienced in anti-cancer treatment. Must confirm NTRK fusion gene (for solid tumors) or ROS1-positive status (for NSCLC) before treatment.

Recommended Dosage

Oral administration. Swallow capsules whole (do not open/dissolve). May take with/without food, but avoid grapefruit/grapefruit juice.

Adults: 600 mg once daily
Pediatric (12+ years): 300 mg/m² once daily (see dosage tables)

Treatment Duration

Continue until disease progression or intolerable toxicity occurs.

Dosage Adjustments

Detailed dosage adjustment tables available for:

Adult dose reduction plan
Pediatric dose reduction scheme
Adjustments for specific adverse reactions
Special populations (elderly, renal/hepatic impairment)

For complete dosage information, see Entrectinib dose guidelines.

Side Effects

Most common adverse reactions (≥20%): fatigue, constipation, dysgeusia, edema, dizziness, diarrhea, nausea, hypoesthesia, dyspnea, anemia, weight gain, increased serum creatinine, pain, cognitive impairment, vomiting, cough, fever.

Serious adverse reactions (≥2%): pulmonary infection (5.2%), dyspnea (4.6%), cognitive impairment (3.8%), pleural effusion (3.0%), fracture (2.4%).

4.6% of patients permanently discontinued treatment due to adverse reactions.

For complete safety information, see Entrectinib side effects.

Storage

Sealed and stored no more than 30℃.

For complete storage information, see Entrectinib package insert.

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Entrectinib 100mg*60 Capsules for NTRK Fusion Solid Tumors

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