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Cabozantinib 60mg Tablets for Kidney Thyroid Liver Cancer Treatment

Name: Cabozantinib 60mg Tablets for Kidney Thyroid Liver Cancer Treatment
Brand: GIVE LIFE TIME LIMITED
SKU: XL-184
Price: 55342706 USD
Availability: InStock

Brand Name:	Cabozanix
Model Number:	XL-184
MOQ:	1 PCS
Price:	Please contact a specialist WhatsApp：55342706
Delivery Time:	Negotiable
Payment Terms:	Western Union,MoneyGram,T/T

Detail Information

Product Description

Detail Information

Place of Origin:

Bangladesh

Specifications::

60mg*30 Tablets/bottle/box

Indications:

Kidney Cancer, Thyroid Cancer, Liver Cancer, Soft Tissue Sarcoma, Non-small Cell Lung Cancer, Prostate Cancer, Breast Cancer, Ovarian Cancer, Bowel Cancer

Target:

RET、MET、VEGFR-1,2,3、KIT

Product Name:

Cabozantinib

Recommended Dose:

Please Follow Doctor's Advice

Storage:

Store Cabozantinib At 20°C To 25°C (68°F To 77°F); Excursions Allowed From 15°C To 30°C (59°F To 86°F).

Packaging Details:

Negotiable

Supply Ability:

Negotiable

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Product Description

Cabozantinib XL-184 (Cabozanix) 60mg Tablets

Product Specifications

Attribute	Value
Specifications	60mg*30 tablets/bottle/box
Indications	Kidney cancer, thyroid cancer, liver cancer, soft tissue sarcoma, non-small cell lung cancer, prostate cancer, breast cancer, ovarian cancer, bowel cancer
Target	RET, MET, VEGFR-1,2,3, KIT
Recommended Dose	Please follow doctor's advice
Storage	Store at 20°C to 25°C (68°F to 77°F); excursions allowed from 15°C to 30°C (59°F to 86°F)

Description

Generic name: cabozantinib

Other names: cabozantinib/XL184

Indications

Treatment of progressive, unresectable locally advanced or metastatic medullary thyroid cancer and advanced kidney cancer that has failed Sutent.

Dosage and Administration

Recommended dosage: 60 mg daily. Do not take with food. Avoid eating for at least 2 hours before and 1 hour after taking.

Swallow tablets whole; do not crush. Continue treatment until clinical benefit ceases or unacceptable toxicity occurs.

Dosage Adjustments

Discontinue 28 days before scheduled surgery
For Grade 4 adverse reactions or intolerable Grade 2-3 reactions, withhold and reduce dose
Permanently discontinue for severe bleeding, arterial thromboembolic events, or uncontrolled hypertension

Warnings and Precautions

Bleeding: Serious bleeding occurred in 2.1% of patients. Do not use in patients with severe bleeding risk.

GI Perforation/Fistula: Reported in 0.9-1.2% of patients. Monitor closely and discontinue if occurs.

Thrombotic Events: Increased incidence of venous (7.3%) and arterial (0.9%) thromboembolism.

Hypertension: Occurred in 37% of patients (15% ≥ grade 3). Monitor blood pressure regularly.

Diarrhea: Occurred in 74% of patients (11% grade 3). Manage with antidiarrheals and dose reduction.

Adverse Reactions

Most common (≥25%): diarrhea, fatigue, nausea, anorexia, palmoplantar erythrodysesthesia syndrome (PPES), hypertension, vomiting, weight loss, constipation.

Special Populations

Pregnancy: May cause fetal harm. Use effective contraception during and for 4 months after treatment
Breastfeeding: Avoid during treatment and for 4 months after final dose
Hepatic Impairment: Reduce dose for mild-moderate impairment. Avoid in severe impairment
Elderly: No significant differences in safety/efficacy observed

Additional Information

Cabozantinib Mechanism of Action

Cabozantinib Side Effects

Cabozantinib Package Insert

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