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Chest Lung Cancer Drugs
Created with Pixso. Afatinib Maleate Tablets 40mg Irreversible EGFR HER2 HER4 TKI Blocker for First Line NSCLC Treatment

Afatinib Maleate Tablets 40mg Irreversible EGFR HER2 HER4 TKI Blocker for First Line NSCLC Treatment

Brand Name: Sichuan Kelun Pharmaceutical Co., Ltd.
Model Number: Afatinib KL-20213350
MOQ: Negotiable
Price: Please contact a specialist WhatsApp:55342706
Delivery Time: Negotiable
Payment Terms: Western Union,MoneyGram,T/T
Detail Information
Place of Origin:
Chengdu, Sichuan, China
Certification:
NMPA/GMP
Active Ingredient:
Afatinib Maleate
Dosage Form:
Tablets
Strength:
40mg
Tablet Count:
30 Tablets
Storage Temperature:
Below 30C
Shelf Life:
24 Months
Packaging Details:
Negotiable
Supply Ability:
Negotiable
Highlight:

Irreversible Pan ErbB TKI

,

EGFR TKI First Line NSCLC

,

Uncommon EGFR Mutation Treatment

Product Description
Afatinib Maleate 40mg x 30 Tablets
Product Name

Generic Name: Afatinib Maleate

Brand Name: Kejixin

Specification: 40mg x 30 Tablets

Active Ingredient

Afatinib Maleate

Indications

First-line EGFR mutation-positive NSCLC (exon 19 del, L858R).

Squamous NSCLC after platinum therapy.

Uncommon EGFR mutations.

Mechanism of Action

Irreversible covalent ErbB family (EGFR/HER2/ErbB4) blocker.

Sustained target inhibition with broad spectrum coverage vs first-gen reversible TKIs.

Dosage and Administration

40mg once daily on empty stomach.

Escalate to 50mg if tolerated.

Reduce to 30mg then 20mg for toxicity.

Adverse Reactions

Diarrhea (95% G1-3 22%), rash (89%), stomatitis (71%), paronychia.

ILD (1-2%, 0.5% fatal), hepatotoxicity, keratitis.

Storage

Store below 30C.

Keep out of reach of children.

Shelf Life

24 months

Approval: H20213350